Jonathan Sean Lowe (born March 29, 1971) is a retired Major League Baseball pitcher. He played during seven seasons at the major league level for the St. Louis Cardinals, Chicago White Sox, Pittsburgh Pirates, Colorado Rockies, and Kansas City Royals. He was drafted by the Cardinals in the 1st round (15th pick) of the 1992 amateur draft. Lowe finished his seven-year MLB career with a 23-15 record, a 4.95 ERA and 288 strikeouts. He was primarily used in middle relief during his career. Lowe played his first professional season with their Class A (Short Season) Hamilton Redbirds in 1992, and his last with Kansas City and their Triple-A Omaha Royals in 2003. Lowe's unique spot in baseball immortality occurred 16 June 2001, against the St. Louis Cardinals, when Albert Pujols recorded his first, and what may yet be his only, sacrifice bunt against Lowe.

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