Muffin Spencer-Devlin (born October 25, 1953) is an American professional golfer who played on the LPGA Tour.

She was born in Piqua, Ohio and joined the LPGA in 1979. She is openly lesbian.

Spencer-Devlin made a cameo appearance as a member of Starfleet Medical in the feature film Star Trek Generations that was released in 1994 and made a brief appearance in "The Chute", the third episode of the 1995 series Star Trek: Voyager.