Seán Keane may refer to:

• Seán Keane (fiddler) (born 1946), fiddle player of The Chieftains
• Seán Keane (singer) (born 1961), Irish folk singer; brother of singer Dolores Keane
• Seán Keane (Irish politician) (1899-1953), Irish Labour Party politician represented Cork East

[ Source: Wikipedia ]