College career

In 2005, as a freshman, Manningham recorded 27 receptions for 433 yards and six touchdowns, including the game-winning catch as time expired in the game against Penn State, handing the Nittany Lions their only loss that season.

Manningham finished 2006 with a total 38 receptions 703 yards and nine touchdowns. He was named Big Ten Offensive Player of the Week two weeks in a row, first against Notre Dame and then against Wisconsin. During the sixth game of the season against Michigan State, Manningham injured his knee and underwent arthroscopic knee surgery on October 10. Manningham made his first game appearance after the injury as a reserve wide receiver on November 4 against Ball State.

Manningham had a total of 72 receptions for 1,174 yards and 12 touchdowns in 2007.

After the 2007 season, Manningham opted to forgo his eligibility for his senior year in 2008 and entered the NFL Draft. He finished his career at Michigan with 137 receptions for 2,310 yards and 27 touchdowns. Those marks placed him ninth, fifth, and fourth, respectively, in school history.

Professional career

Pre-draft

Manningham had reportedly been removed from "multiple teams'" draft boards due to alleged marijuana use in college. Mario denied testing positive initially, then sent a letter to all 32 teams admitting he lied. Manningham claims he failed two drug tests at Michigan. Bob McGinn of the Milwaukee Journal-Sentinel reported that Manningham scored a 6 out of 50 on the Wonderlic exam. This along with several other problems caused his draft value to drop.

New York Giants

2008 season

Manningham was selected in the third round (95th overall) of the 2008 NFL Draft by the New York Giants. During rookie training camp, Manningham noted that he looked forward to playing with fellow former Michigan Wolverine Amani Toomer. Manningham signed a four-year deal worth up to $2.3 million. Manningham made his first reception on October 5, 2008 in a game against the Seattle Seahawks which the Giants won by a score of 44-6.

2009 season

Manningham worked on his punt return abilities and competed for the punt returner spot in 2009.

Manningham kicked off the 2009 season by catching three passes for 58 yards and a touchdown en route to the Giants' 23-17 win over the Washington Redskins. He followed this up by catching 10 passes for 150 yards and a juggling sliding catch for a touchdown in the Giants' 33-31 win over the Dallas Cowboys.

Manningham became the starting wide receiver opposite Steve Smith after fellow receiver Domenik Hixon was injured in a week 2 game against the Dallas Cowboys.

2011 season

On February 5, 2012, Manningham made a catch in the fourth quarter of Super Bowl XLVI to set up the win against the Patriots. Trailing by 2 points with 3 minutes 46 seconds remaining, the Giants started the winning drive. Eli Manning lofted a long pass down the left sideline to Mario Manningham, who kept his feet in-bounds by a fraction of an inch with two defenders around him for a gain of 38 yards. The Giants went on to beat the New England Patriots 21-17. Manningham ended the game with 5 catches for 73 yards.

San Francisco 49ers

2012 season

Manningham signed a two-year, $7.375 million contract with the San Francisco 49ers on March 22, 2012. On December 23, 2012, he tore his ACL and PCL in his left knee against division rival, the Seattle Seahawks, in a game the 49ers lost 42-13. The next day, the 49ers stated that Manningham would be out for the season. Without Manningham the 49ers reached Super Bowl XLVII, but lost to the Baltimore Ravens 34-31.

2013 season

On August 27, 2013, the 49ers placed Manningham on the reserve/physically unable to perform list. Manningham was activated by the 49ers on November 4, 2013 after recovering from the injury sustained against the Seahawks. After seeing limited duty, Manningham was placed on the injured reserve list on December 27, 2013, ending his season.

Second stint with Giants

On March 18, 2014, Manningham signed a one-year contract to return to the New York Giants. After straining his calf in the last preseason game, he was placed on injured reserve and then released.

Career Statistics

Regular season

Season	Team	Games		Receiving					Rushing					Fumbles
		GP	GS	Rec	Yds	Avg	Lng	TD	Att	Yds	Avg	Lng	TD	FUM	Lost
2013	San Francisco 49ers	6	3	9	85	9.4	14	0	-	-	-	-	-	-	-
2012	San Francisco 49ers	11	9	41	449	11.0	40	1	3	64	21.3	29	0	1	0
2011	New York Giants	12	10	39	523	13.4	47T	4	-	-	-	-	-	-	-
2010	New York Giants	16	8	60	944	15.7	92T	9	1	2	2.0	2	0	1	1
2009	New York Giants	14	10	57	822	14.4	49	5	-	-	-	-	-	1	1
2008	New York Giants	7	0	4	26	6.5	11	0	1	-12	-12.0	-12	0	-	-
	Total	67	40	210	2,849	13.5	92	19	5	54	10.8	29	0	3	2

Postseason

Season	Team	Games		Receiving					Rushing					Fumbles
		GP	GS	Rec	Yds	Avg	Lng	TD	Att	Yds	Avg	Lng	TD	FUM	Lost
2011	New York Giants	4	2	13	189	14.5	38	3	0	0	0.0	0	0	0	0
	Total	4	2	13	189	14.5	38	3	0	0	0.0	0	0	0	0

[ Source: Wikipedia ]