Early life

Caplan was born and raised in the Miracle Mile district of Los Angeles, California. Her family were Reform Jews. Her father was a lawyer and her mother was a political aide. She was the youngest of three children with an older brother and sister. Her mother died of illness when she was 13 years old. Her uncle is publicist Howard Bragman. Caplan attended Alexander Hamilton High School, and was a student at the school's Academy of Music. She first focused on playing the piano, then later decided to pursue drama. She was also on her school's soccer team. She graduated in 2000, but did not attend college because it was time consuming and she wanted to focus on acting.

Career

Caplan began her acting career in 1999, first playing a girl named Sara in the critically acclaimed series Freaks and Geeks. Due to her performance, her character became the girlfriend of Jason Segel's character. She then had a series of guest appearances on numerous shows, and appeared in Jason Mraz's music video "You and I Both". In 2000 she appeared in her first film From Where I Sit which was released straight to television. In 2001, she played Tina Greer in an episode of Smallville, and reprised her role on the show in 2003. She appeared in two episodes of the ABC series Once and Again. In 2003, she starred in the television series The Pitts, playing Faith Pitt. She gained wider notice for playing Janis Ian in the 2004 film Mean Girls. She played Avery Bishop in the second season of Tru Calling.

In 2005, Caplan played troubled sister Marjee Sorelli in Related, a one-hour comedy-drama on The WB that was canceled after one season. In 2006, she starred as Sara Weller in the thriller film Love is the Drug and was named one of "10 Actors to Watch" by Variety. After Related ended, Caplan was cast in the CBS sitcom The Class, which premiered in September 2006 and lasted for one season. She played Kat Warbler, one of several elementary school friends that reunite after 20 years.

In 2008, Caplan played Marlena Diamond in the film Cloverfield and was nominated for a Saturn Award for Best Supporting Actress. She also appeared as Ami in the romantic comedy My Best Friend's Girl. Later that year, she guest starred as Amy Burley on the HBO vampire show True Blood. She is the voice of Faith Pitt in the animated version of The Pitts, which premiered in 2009. She also appeared in the critically acclaimed Starz ensemble comedy Party Down, playing a struggling comedian who is part of a catering crew. In 2010, she appeared in 127 Hours.

In early 2012, Caplan premiered two films at the Sundance Film Festival: Save the Date and Bachelorette. Also in 2012, she appeared as Julia in several episodes of the Fox sitcom New Girl.

She played Agent Lacey in the 2014 film The Interview.

Masters of Sex (2013-present)

In 2013, she began playing 1960s human sexuality pioneer Virginia Johnson on the Showtime series Masters of Sex. The first season aired to critical acclaim and strong ratings. Caplan also provided her own vocals for a cover version of the song "You Don't Know Me" in the Masters of Sex episode "Phallic Victories". Her performance on the show was well-reviewed, and on July 10, 2014, she was nominated for the Primetime Emmy Award for Outstanding Lead Actress in a Drama Series.

Caplan was cast in her role as Virginia Johnson before they signed her co-star Michael Sheen as William H. Masters because he was busy working on another production. Producer Sarah Timberman said of Caplan, "the minute we met Lizzie we thought that she just embodied so much of the spirit of Virginia Johnson." Caplan also stated herself that as a single woman pursuing her career above a family, she identified with many of Johnson's characteristics. Once she met the producers, it took several months before Caplan was officially signed, and she turned down several other roles in the meantime.

Virginia Johnson worked alongside William H. Masters as they completed research of human sexual response and sexual dysfunction beginning in the late 1950s. To learn about the characters they were portraying Caplan along with her other co-stars read Thomas Maier's 2009 biography Masters of Sex. The author also allowed Caplan to listen to some of the his interview tapes with Johnson. Caplan also attempted to spend some time with Johnson before she died in 2013, but Johnson was ambivalent about the development of the show. It was the first time she portrayed a real person and Caplan mentioned in an interview that she felt a "deep responsibility" to Johnson, but that she had some wiggle room because most people have no idea what Johnson looked or sounded like. Maier stated that the developers of the show have remained mostly accurate to his book and have included other events that are historically relevant to St. Louis, where the series takes place and where Masters and Johnson lived.

Her portrayal of American sexologist Virginia Johnson was her first serious dramatic role and resulted in nominations for an Emmy Award and a Critics' Choice Award for Outstanding Lead Actress.

Due to the large number of sex scenes in Masters of Sex, she has become well known for being portrayed in this way. In many interviews Caplan has stated that although the amount of nude scenes in the show were uncomfortable at first, she has gotten "as comfortable as possible" and actually enjoys shooting the scenes.

Personal life

Caplan dated actor Matthew Perry from 2006 to 2012. She is the godmother of the daughter of actress Busy Philipps and screenwriter Marc Silverstein.

Filmography

Film

Year	Title	Role	Notes
2002	Orange County	Party girl
2003	Hardcore Action News	Lizzy Lyons	Short film
2004	Mean Girls	Janis Ian
2006	Love Is the Drug	Sara Weller
2007	Crashing	Jacqueline
2008	Cloverfield	Marlena Diamond	Nominated—Saturn Award for Best Supporting Actress
2008	My Best Friend's Girl	Ami
2009	Crossing Over	Marla
2010	Successful Alcoholics	Lindsay	Short film
2010	Hot Tub Time Machine	April Drennan	Nominated—Teen Choice Award for Choice Movie Actress: Comedy
2010	Last Rites of Ransom Pride, TheThe Last Rites of Ransom Pride	Juliette Flowers
2010	127 Hours	Sonja Ralston
2011	High Road	Sheila
2012	Save the Date	Sarah
2012	Bachelorette	Gena
2012	3,2,1... Frankie Go Boom	Lassie
2012	Queens of Country	Jolene Gillis
2012	Marvel One-Shot: Item 47	Claire	Short film
2014	Interview, TheThe Interview	Agent Lacey
2015	The Night Before	Diana
2016	Now You See Me 2	Lula	Post-production
2016	Allied	Bridget	Filming

Television

Year	Title	Role	Notes
1999-2000	Freaks and Geeks	Sara	4 episodes
2000	From Where I Sit	Lily	Television film
2001	Undeclared	Beautiful girl	Episode: "Prototype"
2001-2003	Smallville	Tina Greer	2 episodes
2001	Once and Again	Sarah	Episode: "Tough Love"
2002	Everybody's Doing It	Angela	Television film
2003	Pitts, TheThe Pitts	Faith Pitt	7 episodes
2005	Tru Calling	Avery Bishop	4 episodes
2005-2006	Related	Marjee Sorelli	18 episodes
2006-2009	American Dad!	Debbie (voice)	4 episodes
2006-2007	Class, TheThe Class	Kat Warbler	19 episodes
2008	True Blood	Amy Burley	6 episodes
2008	Life & Times of Tim, TheThe Life & Times of Tim	N/A	Episode: "Insurmountable High Score/Tim vs. the Baby"
2009-2010	Party Down	Casey Klein	20 episodes
2010-2011	Childrens Hospital	Harmony / Casey Klein	2 episodes
2011	Cleveland Show, TheThe Cleveland Show	Patty Donner (voice)	Episode: "The Essence of Cleveland"
2011	Mr. Sunshine	Vivian Cornelli	Episode: "Ben and Vivian"
2011	Wainy Days	Arielle	Episode: "Kelly and Arielle - Part 2"
2012	New Girl	Julia	4 episodes
2013	Newsreaders	Anya Turpo	Episode: "Hedge Fun"
2013-present	Masters of Sex	Virginia Johnson	Main role; also producer Nominated—Critics' Choice Television Award for Best Actress in a Drama Series Nominated—Primetime Emmy Award for Outstanding Lead Actress in a Drama Series Nominated—Satellite Award for Best Actress - Television Series Drama
2013-2014	League, TheThe League	Rebecca Ruxin	3 episodes
2014	Kroll Show	Signing Bonus Contestant #1	Episode: "Krolling Around with Nick Klown"
2014	Comedy Bang! Bang!	Herself	Episode: "Lizzy Caplan Wears All Black & Powder Blue Espadrilles"

[ Source: Wikipedia ]