James Griffin may refer to:

• Jimmy Griffin (James Arthur Griffin, 1943-2005), American musician, member of Bread
• James D. Griffin (1929-2008), former American politician and mayor of Buffalo, New York
• James Griffin (scriptwriter), New Zealand scriptwriter
• James Griffin (American football) (born 1961), American football player
• James Bennett Griffin (1905-1997), former American archaeologist
• James J. Griffin (born 1949), author
• James Griffin (philosopher) (born 1933), former White's Professor of Moral Philosophy at the University of Oxford
• James Griffin (songwriter), Australian singer / songwriter
• James Griffin (Irish politician) (1899-1959), Irish Fianna Fáil politician from Meath
• James Aloysius Griffin (1883-1948), American prelate of the Roman Catholic Church
• James Anthony Griffin (born 1934), American prelate of the Roman Catholic Church
• Jim Griffin (footballer) (born 1967), Scottish footballer who played for Motherwell FC in the 1991 Scottish Cup Final
• James Griffin (ice hockey) (born 1993), British ice hockey player

[ Source: Wikipedia ]