Brian Walker may refer to:

• Brian Walker (American football) (born 1972), former American football safety in the National Football League
• Brian Walker (Arena football) (born 1984), American football player who plays for the Jacksonville Sharks
• Brian Walker (baseball), American baseball catcher
• Brian Walker (ecologist), scientist working on ecological sustainability and resilience in social-ecological systems
• Brian Walker (toy inventor), toy inventor from Bend, Oregon

[ Source: Wikipedia ]